Principal Investigator

Dr. Tony Hadibarata
Universiti Teknologi Malaysia (UTM), Malaysia

ASEAN Co-Investigator

Institut Teknologi Sepuluh Nopember (ITS)

Japanese Co-Investigator

Osaka University

Awarded year



Collaborative Research Program for Common Regional Issues (CRC)


Environmental Engineering


Recently, environmental research has increasingly focused on endocrine-disrupting chemicals (EDCs), which have proven to cause fertility reduction, feminization and other adverse effects in male animals within natural and laboratory settings. Among the endocrine disruptors, 17b-estradiol, estrone and 17a-ethynylestradiol are the major contributors of estrogenic activity in the environment. Other chemicals such as those carrying a phenolic group including nonylphenol, octylphenol and bisphenol A, and phytoestrogen group are also suspected to disrupt animal endocrine systems. Hormone disrupting compounds enter the environment in many product formulations. There are more than 87,000 known chemicals which may be considered amongst EDCs. Although the occurrence and fate of EDCs have been profoundly monitored in America, Europe and other Asian countries, there is still a lack of information on estrogenicity in other parts of the world such developing countries such as Indonesia and Malaysia. . Focusing our attention in Malaysia and Indonesia rivers, Malaysian peninsula and Jawa Island is one of the most vulnerable regions of the world to the global change due to climatic conditions characterized by frequent droughts and other pressures on water resources. Some of rivers (Johor River, Klang River, Berantas River, Citarum River and Bengawan Solo River) are characterized by important fluctuations in the flow rates and heavy contamination pressures from extensive urban, industrial and agricultural activities. This translates in contamination levels most often higher than those in other country region

Project at glance